منابع مشابه
Aspirin resistance in healthy volunteers.
We have read with great enthusiasm the recently published article by Marcel Tschopp and Walter H. Reinhart entitled “Platelet aggregation under high shear conditions during and after a 28-day administration of 100 mg acetylsalicylic acid in healthy volunteers” [1]. They concluded that platelet function as measured by the PFA-100 is not inhibited significantly after a single dose of 100 mg aspir...
متن کاملAspirin responsiveness in healthy volunteers measured with multiple assay platforms.
BACKGROUND We evaluated the sensitivity, precision, and concordance of 4 assays designed to detect aspirin responsiveness or resistance. METHODS Twenty-nine healthy laboratory volunteers took 80 mg aspirin for 7 days, and a subset of volunteers took 325 mg aspirin for an additional 7 days. We measured platelet function by light transmission aggregometry with arachidonic acid, PFA-100, and Ver...
متن کاملSpinopelvic Parameters among Healthy Volunteers in Iran
Background: Recently, in approach to spinal pathologies, the whole spine should be considered as a biomechanicalunit. Studies have shown the great importance of sagittal and coronal balance and the relationship between the variousparts of spine together and pelvis. Former studies have shown a close relationship between spinopelvic parametersand sagittal balance. A complete und...
متن کاملComparison of antiplatelet activity of garlic tablets with cardio-protective dose of aspirin in healthy volunteers: a randomized clinical trial
Objective: Some of the adverse effects of aspirin including peptic ulcers, gastrointestinal bleeding and aspirin resistance compelled researchers to find a suitable alternative with fewer adverse effects. In this clinical trial, we aimed to find the effective antiplatelet dose of garlic. Materials and Methods: This randomized controlled clinical trial (RCT) was conducted on 62 healthy volunteer...
متن کاملCelecoxib Does Not Attenuate the Antiplatelet Effects of Aspirin and Clopidogrel in Healthy Volunteers
BACKGROUND AND OBJECTIVES The prevalence of arthritis, which is often treated with celecoxib, is high in patients with coronary artery disease. Furthermore, celecoxib has been reported to reduce restenosis after coronary stenting by inhibiting expression of the proto-oncogene Akt. A concern is that celecoxib increases thrombogenicity by inhibiting the synthesis of prostacyclin in endothelial ce...
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ژورنال
عنوان ژورنال: Clinical Hemorheology and Microcirculation
سال: 2009
ISSN: 1386-0291
DOI: 10.3233/ch-2009-1214